DIM

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Description

Hormones (especially estrogen) are critically important in human development and tissue repair. However, estrogen’s proliferative effects must be balanced and controlled for optimal health. Therefore, to ensure proper hormonal balance, estrogen synthesis and detoxification should be supported. Estrogen has several downstream metabolites, of which some are beneficial while others possess potentially harmful biological activity. By keeping hormones in balance and ensuring the body can process estrogen properly, cruciferous vegetable metabolites (i.e., I3C and DIM) work together to maintain cellular health.

Optimum DIM is a targeted supplement that combines the synergistic benefits of the cruciferous vegetable metabolites indole-3-carbinol (I3C) and 3-3’-diindolylmethane (DIM) to support balanced estrogen metabolism.

Many of the health benefits derived from eating cruciferous vegetables (e.g., cabbage, Brussels sprouts, broccoli, etc.), especially those shown to be beneficial for breast and prostate health, are thought to be derived from the group of secondary metabolites known as glucosinolates. When these vegetables are cut, crushed or chewed, the action of the enzyme myrosinase (released from the plant cells) hydrolysis these glucosinolates into other compounds. For instance, glucosinolates from broccoli and Brussels sprouts readily convert into I3C when consumed. I3C can then be further converted via stomach acid into other health-promoting compounds, including DIM. These compounds have generally been thought to be responsible for the various cellular activities that lead to hormone health.

Package Information

60 Capsules

Supplement Facts

Product Data

Indole-3-carbinol (I3C) and diindolylmethane (DIM) are natural metabolites of compounds found in numerous vegetables from the Brassicaceae family. Both I3C and DIM, as well as many other I3C metabolites, have been shown to impact metabolic shifts and cellular activities for improved health outcomes. I3C and DIM have been shown to induce some phase I and phase II biotransformation genes in preclinical models through pathways such as Nrf2, suggesting I3C and DIM may have a role in detoxification. Additionally, both I3C and DIM have been shown in vitro to decrease aromatase expression, the enzyme that converts androgens to estrogen.

Recommendations

Consult your healthcare professional before using any supplement if pregnant, nursing, taking medications, or for any use by a minor. Keep all supplements out of the reach of children. None of the statements made on any products sold by New Leaf Health have been evaluated or approved by the F.D.A. These products are not intended to diagnose, treat, cure, or prevent any disease. For nutritional use only. Please consult a healthcare professional for dosage recommendations.