Description
Hormones (especially estrogen) are critically important in human development and tissue repair. However, estrogen’s proliferative effects must be balanced and controlled for optimal health. Therefore, to ensure proper hormonal balance, estrogen synthesis and detoxification should be supported. Estrogen has several downstream metabolites, of which some are beneficial while others possess potentially harmful biological activity. By keeping hormones in balance and ensuring the body can process estrogen properly, cruciferous vegetable metabolites (i.e., I3C and DIM) work together to maintain cellular health.
Optimum DIM is a targeted supplement that combines the synergistic benefits of the cruciferous vegetable metabolites indole-3-carbinol (I3C) and 3-3’-diindolylmethane (DIM) to support balanced estrogen metabolism.
Many of the health benefits derived from eating cruciferous vegetables (e.g., cabbage, Brussels sprouts, broccoli, etc.), especially those shown to be beneficial for breast and prostate health, are thought to be derived from the group of secondary metabolites known as glucosinolates. When these vegetables are cut, crushed or chewed, the action of the enzyme myrosinase (released from the plant cells) hydrolysis these glucosinolates into other compounds. For instance, glucosinolates from broccoli and Brussels sprouts readily convert into I3C when consumed. I3C can then be further converted via stomach acid into other health-promoting compounds, including DIM. These compounds have generally been thought to be responsible for the various cellular activities that lead to hormone health.